Resource Library

What is Hepatitis C?

Hepatitis C is a liver infection caused by the hepatitis C virus (HCV). Infection with the virus causes liver inflammation and can cause liver disease.

What are the signs or symptoms of hepatitis C?

A lot of people with hepatitis C won’t experience any symptoms. Other people may get flu-like symptoms, nausea, or abdominal pain pretty soon after getting infected. During the first two to six months after getting infected, some people clear the virus from their body on their own. Others go on to develop a chronic hepatitis C infection, which can result in cirrhosis and liver cancer after many years, if untreated.

How do I get tested for hepatitis C?

Blood tests are used to diagnose hepatitis C. An HCV antibody test is used initially, and if positive, an HCV RNA test is used to confirm presence of the virus itself. If you’re living with HIV, you should have a hepatitis C test at least once a year. Testing every six months is recommended if:

  • You have had more than 10 partners in the past six months
  • You have had condomless anal sex
  • You have used recreational drugs
  • You have had group sex
I have/had hepatitis C. What should I know?

There is a cure for hepatitis C. Find out more about our hepatitis C treatment and cure services.

If you have hepatitis C now or have had it in the past, you have hepatitis C antibodies in your blood. But even if your body clears the infection on its own, you could get re-infected if you come into contact with the virus again. You don’t develop immunity to the hepatitis C virus (unlike hepatitis A and hepatitis B).

For people who don’t clear the virus on their own, the infection will be monitored with liver function tests.

If you are living with hepatitis C:

  • Be careful if you get blood on anything. Clean your blood off surfaces carefully if you cut yourself. Wear disposable gloves and use household bleach to clean up blood spots or spills. Then use cold water to rinse the surface.
  • If you cut yourself or have some other skin wound, cover it with sterile, waterproof dressing.
  • Put any tissues, napkins, bandages, or wound-care items exposed to your body fluids in a sealed or knotted plastic bag before throwing them away.
  • If you get blood stains on your clothes, rinse the blood out first and then wash your clothes on a regular wash cycle.
  • Wear a condom and use a water-based lube during sex.

Hepatitis C & HIV Coinfection

People living with HIV are more likely to have been exposed to hepatitis C than people who are HIV-negative.

If you’re living with hepatitis C and HIV:

  • You may have more difficulty getting an accurate hepatitis C test result (i.e., you might be more likely to get a false-negative or indeterminate test reading, particularly if your CD4 count is low.)
  • You may have a higher concentration of the hepatitis C virus in your body fluids
  • You may have higher HIV viral loads but probably won’t experience faster HIV disease progression
  • You can safely treat both infections, although usually not beginning at the same time since this can make side effects worse. (Getting HIV under control is usually the first priority.)
  • You must have your liver enzymes monitored regularly since HIV medications can cause liver inflammation or damage.
How is hepatitis C treated?

Since 2014, newer treatments for hepatitis C have been available that are highly effective at clearing the virus from your body and thereby prevent the virus from causing cirrhosis (scarring) of the liver, liver cancer and liver failure. These new treatment options will work for you even if older treatments didn’t work for you. Newer treatments are extremely well tolerated, with few side effects and relatively short durations (typically 12 weeks) required to cure hepatitis C.

Though today most can be cured of hepatitis C–since hepatitis C medications work better on some strains of the virus than others– a few individuals may require more intense regimens. But the sooner you are diagnosed, the sooner you can get treated, and you have a better chance of being cured with early treatment. Chronic hepatitis C infection can be monitored with liver function tests. Get tested for hepatitis C.

Some people find complementary therapies and lifestyle changes to be helpful in managing hepatitis C symptoms.

Is hepatitis C contagious?

Hepatitis C is transmitted from contact with infected blood. You can get infected if even a small amount of infected blood gets into your bloodstream. Sharing needles, syringes, or other equipment to inject drugs can transmit HCV. People also get HCV from needlesticks and sharps injuries in healthcare settings.

It’s also possible to transmit hepatitis C by sharing toothbrushes, razors, or tattoo and piercing equipment.

Hepatitis C can also be acquired through sex. More and more gay and bi men and other men who have sex with men — particularly men who have HIV — are getting hepatitis C, even though historically, sexual activity was thought of as a low-risk activity for transmission. Some of these cases might be from sharing injection equipment, but it seems that most are due to sexual transmission.

Hepatitis C transmitted during sex usually happens during condomless anal sex. Risk of transmission goes up with any sexual activity that damages the lining of the anus — such as fisting, sex sessions that last a long time or rough sex. Group sex, party drug use before sex and using unwashed sex toys can also put you at risk of hepatitis C if you’re exposed to blood or you have breaks in your skin.

The hepatitis C virus also lives in semen, but whether or not this adds to the risk of transmitting hepatitis C during condomless anal sex is unknown.

How can I protect myself from hepatitis C?

There isn’t a vaccine you can get to prevent hepatitis C infection. Here’s what you can do to reduce the likelihood that you’ll get hepatitis C:

  • Use condoms and water- or silicone-based lube during anal sex, especially if there is blood or other STIs. Do not use oil-based lubricants with condoms, as these lubes may cause condoms to break.
  • Wear gloves and use water- or silicone-based lube during fisting
  • Don’t share sex toys with sex partners. Or, put a condom over insertive sex toys and change them between different partners
  • Wash hands and sex toys before and after sex and between partners
  • Don’t share injection equipment like needles, syringes, swabs, spoons, filters, water or tourniquets. Always use new injection equipment.
  • Wash your hands before and after using injection drugs
  • Don’t share personal items like toothbrushes, razors, nail clippers, or nail scissors
  • Make sure body artists use new and sterile equipment if you get tattoos, body piercings or other body art
  • Wear disposable gloves if you give someone first-aid or are cleaning up blood or other body fluids.

Hepatitis C & HIV Coinfection

People living with HIV are more likely to have been exposed to hepatitis C than people who are HIV-negative.

If you’re living with hepatitis C and HIV:

  • You may have more difficulty getting an accurate hepatitis C test result (i.e., you might be more likely to get a false-negative or indeterminate test reading, particularly if your CD4 count is low.)
  • You may have a higher concentration of the hepatitis C virus in your body fluids
  • You may have higher HIV viral loads but probably won’t experience faster HIV disease progression
  • You can safely treat both infections, although usually not beginning at the same time since this can make side effects worse. (Getting HIV under control is usually the first priority.)
  • You must have your liver enzymes monitored regularly since HIV medications can cause liver inflammation or damage.

Related Services

Harm Reduction Center

The Harm Reduction Center is a place of welcome and a pathway to improved health and healing. Located in the Tenderloin/SoMa neighborhood, the Harm Reduction Center provides health services and supplies that help people who inject drugs manage their health, prevent overdose, and stop HIV and hepatitis C transmission.

Visit Us

Hepatitis C Support Groups

We offer a treatment and support group for people enrolled our Hepatitis C Wellness Program. This community-based HCV group provides a time for people to take medication and offers space for people to check in with each other, share their experiences and give and get support. Enroll in the Hepatitis C Wellness Program to join.

Enroll