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Knowing your status is good sexual health

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Substance Use Support, Your Way

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Our Mission

We work to eliminate HIV transmission and extend the longevity of people living with HIV through a network of direct programs and supportive services. We provide sexual health, substance & behavioral health, engagement & retention, and social support services, and advocate at all levels of government for people living with and at risk for HIV.

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The Latest

USPSTF Recommendation for PrEP

Task Force recommends that clinicians offer PrEP to individuals at high risk for HIV acquisition.

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Top tips for more pleasurable bottoming

For all of you out there who have never bottomed because you thought your partner’s penis...

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Parade grand marshal, activist spotlights persistent HIV stigma

After 30-years of community building, parade grand marshal and HIV activist says the end of transmission won’t be over as long as people feel challenged to seek treatment.

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Grassroots power is a critical force in ensuring a compassionate and effective response to the HIV epidemic. Join our HIV Advocacy Network and make your voice heard. Text SFAF to 52886.

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Main Office

1035 Market Street, Suite 400
San Francisco, CA 94103


470 Castro Street
San Francisco, CA 94114

Harm Reduction Center

117 6th Street
San Francisco, CA 94103

Mobile Testing Unit

Hours and locations vary

Mobile Syringe & Health Services

Hours and locations vary