What Is Harm Reduction?
Harm reduction is a way to “meet people where they’re at,” without requiring you to meet certain conditions in order to maintain your health. It’s safety, your way.
Harm reduction approaches to substance use are not strictly abstinence-oriented. Rather, they encourage individuals to examine the connections between their substance use or sexual health and their health and well-being, and to take steps toward any positive change.
Our programs and services are based in harm reduction. Everyone is welcome, no matter what place they’re in, no matter how challenging their life is, no matter how sick they are. It’s a client-centered, person-centered approach.

Syringe Access & Safer Drug Use
We provide safer drug use supplies to people who inject or use other substances in order to prevent the transmission of HIV, hepatitis C and other infectious diseases.

Drug & Alcohol Counseling
We provide non-judgmental, harm reduction-based drug and alcohol counseling and drop-in services for people interested in addressing their substance use. Treatment is a partnership, individually tailored to address each participant’s goals and needs wherever they are in their experience with alcohol and drugs.

Prevent Overdose Fatalities
Opioid overdoses are the leading cause of death in the United States. But you can change that stark statistic with the right training and supplies,. In collaboration with the D.O.P.E. Project, we offer overdose prevention and response training and supplies like fentanyl test strips and Narcan.

Harm Reduction Center Drop-In Group
People who inject or use substances are invited to our harm reduction drop-in group at the Harm Reduction Center. We have snacks, coffee and conversation about reducing the harms that drugs can cause. No judgement, only harm reduction information and caring support for people who use drugs. While you’re there, pick up safer injection and smoking supplies, disposal equipment, overdose prevention and reversal supplies and more.
Our Programs

The Stonewall Project
Counseling for gay, bisexual, queer & trans men interested in changing their relationship to drugs & alcohol.

Syringe Access Services
Safer injection and substance use supplies that prevent the transmission of HIV and HCV.

6th Street Harm Reduction Center Groups
Snacks, coffee and substance use drop-in support.
More on Harm Reduction

Needs assessment report of Latino/x people who use drugs in San Francisco
In 2021/2022, San Francisco AIDS Foundation and the National Harm Reduction Coalition conducted a needs assessment to examine the conditions, challenges, and barriers impacting Latino/x people who use drugs.

What can we do to stop overdose deaths?
Here are a variety of strategies that could help turn the tide on overdose, and save lives of people who use drugs.

Overdose affects us all
We commemorate International Overdose Awareness Day on August 31, and throughout the month of...

How to prevent and respond to overdose
Read steps on how to administer Narcan, get prevention tips, and download our brochure.

Cómo usar Narcan nasal-guía rápida
Todo lo que necesitas saber acerca de cómo administrar Narcan Nasal de 4mg

COVID-19 and Harm Reduction
Information for People Who Use Drugs, Syringe Service Providers, and other Harm Reduction Providers.

Tweaker.org
What started as an awareness campaign about meth and sexual risk-taking now receives nearly 1 million visitors annually.

History of Health: Needle Exchange in San Francisco
The city’s first needle exchange began in 1988 as an act of civil disobedience to improve the health and lives of people who use drugs.