Harm Reduction Center

Located in the Tenderloin/SoMa neighborhood of San Francisco, the Harm Reduction Center provides services and supplies that help you manage your health, prevent overdose, and stop HIV and hepatitis C transmission.

Our services are free and include safer substance use supplies, injection and syringe disposal equipment, overdose prevention training and supplies including naloxone, harm reduction counseling, Suboxone, HIV and STI testing, hepatitis C testing and treatment and other low-barrier services to people who use substances or who inject.

We are a place of welcome and a pathway to improved health and healing.

Harm Reduction Center

117 6th Street (between Mission & Minna)
San Francisco, CA 94103

The Harm Reduction Center is on the east side of 6th Street, between Mission Street and Minna Street. The facility is one floor and is wheelchair accessible. There are no steps up or down from the street.

The 14-Mission bus makes the closest stop one block away at Mission & 6th Street. We are two blocks southeast of where Market Street meets Taylor, Golden Gate, and 6th Streets. Buses that stop nearby are 6-Haight-Parnassus, 7-Haight-Noriega, 9-San Bruno, and 21-Hayes.


Monday: 9 am – 7 pm
Tuesday: 9 am – 1 pm; 4 pm – 7 pm
Wednesday: 9 am – 1 pm; 4 pm – 7 pm
Thursday: 9 am – 7 pm
Friday: 9 am – 1 pm; 4 pm – 7 pm
Saturday: 7 pm – 11 pm
Sunday: Closed

Testing Hours: Tuesday – Friday, 11 am – 1 pm; Saturdays, 7 pm – 11 pm
Hepatitis C linkage and treatment: Tuesdays & Thursdays, 11 am – 1 pm

Groups & Lounges


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Get a list of free events and activities including concerts, films, street festivals, cultural events, lectures, workshops, harm reduction groups, community activism opportunities, mindfulness, wellness and fitness resources and opportunities to see and do art.

Feb 14 - Feb 21

Volunteer with Syringe Access Services

Help reduce transmission of HIV and hepatitis C and provide community-based harm reduction services as a volunteer for Syringe Access Services.


Mobile Syringe & Health Services

Find safer injection and disposal supplies and services that help you manage your health, prevent overdose and stop the transmission of HIV and hepatitis C.