Editor's Note

Depression is a familiar complaint among people living with HIV. Even if physical health has stabilized, symptoms of depression can diminish quality of life and lead to other complications. Lisa Capaldini, M.D., and George Harrison, M.D., present an overview of this common condition and discuss treatment strategies with HIV-positive people in mind. The current state of research on blood sugar abnormalities -- another topical concern -- is laid out in "Insulin Resistance and Diabetes." Our third feature, "Oral Health and HIV," covers a range of issues from cavities and dry mouth to oral cancers. Readers will also find an update on tipranavir, a unique protease inhibitor in late-stage development, and a report on drug resistance in women using antiretroviral agents to prevent mother-to-child HIV transmission.

We invite our readers to consider the following question for next issue's "In Their Own Words" section: What method do you use to stay adherent to your antiretroviral drug regimen? A selection of responses will be published. Please send brief answers to us via e-mail, fax, or post.