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Daily PrEP

Daily PrEP

Strut, 470 Castro Street, is offering limited clinical services available Tuesday – Saturday, 10 am – 4 pm. Walk-in clients are not being seen at this time. Please call the clinic at 415-581-1600 for instructions.

If you have symptoms of a suspected sexually transmitted infection or have had a recent HIV exposure, please call 415-581-1600 and select option #3 to be connected with the nursing team at Magnet. They will be able to coordinate services and testing for you.

If you are currently receiving PrEP or HIV care from our clinical team, we can extend your prescriptions to cover this time period. To request a refill, call our navigation team at 415-437-3450, press option #2. You can also email questions about PrEP to and questions about HIV services to

Daily PrEP involves taking the PrEP medication (Truvada) once per day to prevent HIV infection. Unlike PrEP 2-1-1 there’s no planning around when to take pills if you might have sex. With Daily PrEP, take PrEP once per day, every day.

According to existing recommendations, daily PrEP should be taken for 7 days prior to having anal sex, and for 20 days prior to having vaginal or front hole sex.

Who is daily PrEP for?

PrEP is for people who are HIV-negative and at risk for HIV infection. That can include people who have one or more partners who are living with HIV, people who have one or more partners whose status they don’t know, men who have sex with men, trans and non-binary people who have sex with men, people who have had sex without condoms, people in the sex trade, people who use injection drugs, and other people who may be worried about HIV infection.

If you have sex and have difficulty using condoms or don’t like to use condoms, PrEP is a way you can reduce your risk for HIV. For many people, PrEP reduces worry and anxiety around sex—enabling people to have healthier, safer sex lives.

You can talk to your health provider to find out if you’re a good candidate.

Daily PrEP does not change the way hormones work for people who are trans masculine or trans feminine and taking hormones. Hormones have not been found to eliminate the effectiveness of daily PrEP.

Daily PrEP effectiveness

Daily PrEP works when you take the medication every day. Missing doses is not advised, but may be OK as long as you take at least four or more pills per week if you’re having anal sex. For people having vaginal or front hole sex, it’s even more important not to miss doses.

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