| |
Major mutation,
frequently observed or associated with high-level resistance. Avoid drug
if possible. |
| |
Common
mutation, alone or with other mutations can be associated with resistance.
Use with caution. |
| |
Less frequent
mutation or common polymorphism. Not generally associated with high-level
resistance. |
| |
Drug does
not select for mutation but mutation may cause some degree of cross resistance. |
| * = Experimental
drug with limited or no in vivo clinical resistance data. |
| FTV = Fortovase,
NFV = nelfinavir, RTV = ritonavir, IDV = indinavir, ddI = didanosine |
| ddC = zalcitabine,
3TC = lamivudine, d4T = stavudine, AZT = zidovudine, AMP = amprenavir |